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EMBL-EBI: Introduction to Interpro




Employ InterPro to help you answer your research questions!

This workshop will help you find out why there is a need to automatically annotate proteins, how protein family databases can help meet this challenge, and how InterPro pulls together a number of such databases, allowing you to classify unknown protein sequences and identify their function. The module is a combination of presentations and hands-on practical exercises. You will explore the various features of an InterPro entry, and design a workflow to utilise InterPro in the analysis of real world data.

Also note: This event is part of a series of short introductions focusing on EMBL-EBI resources.



Lorna Richardson, EMBL-EBI

Alex Mitchell, EMBL-EBI


Audience and Prerequisites

  • This module is suitable for researchers who wish to know more about the InterPro resource
  • No previous bioinformatics experience is required, but an undergraduate level understanding of biology would be an advantage
  • Graduate students, Postdocs and Staff members from the University of Cambridge, Affiliated Institutions and other external Institutions or individuals


Syllabus, Tools and Resources

During this course you will learn about:

  • InterPro (
  • Why we need automated tools to annotate protein sequences
  • The difference between pairwise similarity and homology based approaches
  • How the InterPro database is used to assign annotation and GO terms to protein sequences


Learning Objectives

After this course you should be able to:

  • describe the importance of automated annotation of protein sequences
  • use the InterPro database to classify protein sequences based on underlying protein family models
  • interpret the InterPro annotations and associated cross-references



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