Daianna Gonzalez Padilla

I work with Dr. Stephen Burgess lab at the Biostatistics Unit, University of Cambridge on stratified Mendelian Randomization studies to investigate causal factors of cardiovascular disease in women and men.

Biography

I obtained my Honours bachelor's degree in Genomic Sciences at the National Autonomous University of Mexico LCG-UNAM, Mexico in 2024.

In the last few years I’ve been involved in multiple omics projects. At the Lieber Institute for Brain Development (LIBD) I analyzed transcriptomic data to explore brain development and function. At the Karolinska Institutet (KI) I studied genetic variability in genes influencing drug response and toxicity. At Sanger I analyzed single-cell data from iPSC-derived microglia to unveil the genetic architecture of neurodegenerative diseases.

Research

My current research evaluates stratified Mendelian Randomization approaches for the detection of causal disease factors varying across strata of the population (e.g. sexes, ages, and ancestries). In previous multi-omics research, I have identified molecular impacts of drugs on rodent brain, characterized genetic determinants of drug response, and proposed drug targets for neurodegeneration.

Publications

Key publications:

Population-scale variability of the human UDP-glycosyltransferase gene family. | Gonzalez-Padilla, D., Camara, M. D., Lauschke, V. M., & Zhou, Y. (2024).

Molecular impact of nicotine and smoking exposure on the developing and adult mouse brain. | Gonzalez-Padilla, D., Eagles, N. J., Cano, M., Pertea, G., Jaffe, A. E., …, Martinowich, K., & Collado-Torres, L. (2024).

Benchmark of cellular deconvolution methods using a multi-assay reference dataset from postmortem human prefrontal cortex. | Huuki-Myers, L. A., Montgomery, K. D., Kwon, S. H., Cinquemani, S., Eagles, N. J., Gonzalez-Padilla, D., …, Collado-Torres, L. (2024).

Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses. | Tzec-Interian, J. A., Gonzalez-Padilla, D., & Gongora-Castillo, E. B. (2025).

Teaching and Supervisions

Teaching:

2025/2026:

Bulk RNA-seq analysis - Trainer

2024/2025:

Single-cell RNA-seq analysis - Trainer

Biography

Research

Publications

Teaching and Supervisions

Contact Details

Contact us

Contact: bioinfotraining@bio.cam.ac.uk

Bluesky: @bioinfocambs.bsky.social

Mastodon: @BioInfoCambs@genomic.social

Site Privacy & Cookie Policies

Research Informatics Training

Postgraduate Courses by Theme

About Cambridge Centre for Research Informatics Training

Study at Cambridge

About the University

Research at Cambridge