Senior Research Associate Virology and Molecular Plant Pathology
Biography
2016-2020 Senior Research Associate with Professor John Carr working on the effect of virus infection in plants on insect behaviour, Department of Plant Sciences, University of Cambridge
2012-2016 Senior Research Associate with Dr John Carr on the effect of virus infection in plants on pollinator behaviour, Department of Plant Sciences, University of Cambridge
2008-2012 Senior Research Associate with Dr John Carr working on subversion of insect resistance by a viral silencing suppressor, Department of Plant Sciences, University of Cambridge
2004-2008 Leverhulme Fellowship with Dr David Hanke working on the role of phytic acid in virus resistance. Dept of Plant Sciences, Cambridge.
2000-2003 Postdoctoral Fellow with Dr David Hanke working on the role of phytic acid in potato, Department of Plant Sciences, University of Cambridge
2000-2003 Research Fellow of Lucy Cavendish College
1997-2000 Cambridge University Broodbank Independent Research Fellowship investigating the effect of salicylic acid on plant virus movement, Department of Plant Sciences, University of Cambridge
1996-1997 Postdoctoral Fellow with Dr John Carr working on salicylic acid induced resistance to viruses, Department of Plant Sciences, University of Cambridge
1993-1995 Postdoctoral Fellow with Dr A.M. Ashby and Dr Keith Johnstone working on the role of cytokinins in fungal biotrophy, Department of Plant Sciences, University of Cambridge
Qualifications
1989-1992 PhD in Molecular Plant Biology, University College London
1985-1988 BSc Botany and Genetics, University College London
Publications
Key publications:
Effects of the cucumber mosaic virus 2a protein on aphid–plant interactions in Arabidopsis thaliana, 2020, Molecular Plant Pathology
Different plant viruses induce changes in feeding behavior of specialist and generalist aphids on common bean that are likely to enhance virus transmission, 2020, Frontiers in Plant Science
Different plant viruses induce changes in feeding behavior of specialist and generalist aphids on common bean that are likely to enhance virus transmission, 2020, Frontiers in Plant Science
Engineering resistance to virus transmission, 2017, Current Opinion in Virology
The biochemical properties of the two Arabidopsis thaliana isochorismate synthases, 2016, Biochemical Journal
Salicylic acid treatment and expression of an RNA-dependent RNA polymerase 1 transgene inhibit lethal symptoms and meristem invasion during tobacco mosaic virus infection in Nicotiana benthamiana, 2016, BMC Plant Biology
Virus infection of plants alters pollinator preference: A payback for susceptible hosts? 2016, PLOS Pathogens
RNA-dependent RNA polymerase 1 in potato (Solanum tuberosum) and its relationship to other plant RNA-dependent RNA polymerases, 2016, Scientific Reports
Salicylic acid treatment and expression of an RNA-dependent RNA polymerase 1 transgene inhibits lethal symptoms and meristem invasion during tobacco mosaic virus infection in Nicotiana benthamiana, 2016, BMC Plant Biology
Domains of the cucumber mosaic virus 2b silencing suppressor protein affecting inhibition of salicylic acid-induced resistance and priming of salicylic acid accumulation during infection, 2014, Journal of General Virology
Interference with jasmonic acid- regulated gene expression is a general property of viral suppressors of RNA silencing but only partly explains virus-induced changes in plant-aphid interactions, 2014, Journal of General Virology
A trio of viral proteins tunes aphid-plant interactions in Arabidopsis thaliana, 2013, PLOS One
Abnormal glycosphingolipid mannosylation triggers salicylic acid-mediated responses in Arabidopsis, 2013, The Plant Cell
A viral RNA silencing suppressor interferes with abscisic acid-mediated signalling and induces drought tolerance in Arabidopsis thaliana, 2012, Molecular Plant Pathology
Disruption of two defensive signaling pathways by a viral RNA silencing suppressor, 2010, Molecular Plant-Microbe Interactions
The effects of extracellular adenosine 5'-triphosphate on the tobacco proteome, 2010, Proteomics
Extracellular ATP is a regulator of pathogen defence in plants, 2009, The Plant Journal
A role for inositol hexakisphosphate in the maintenance of basal resistance to plant pathogens, 2008, The Plant Journal
Allopurinol, an inhibitor of purine catabolism, enhances susceptibility of tobacco to Tobacco mosaic virus, 2008, Virus Research
Induced Resistance Mechanisms Chapter in Natural Resistance Mechanisms of Plants to Viruses, 2006
Mechanisms involved in Plant Resistance to Viruses Chapter in Induced Resistance to Plant Pathogens, 2005
Genetic modification of alternative respiration has differential effects on Antimycin A- versus salicylic acid-induced resistance to Tobacco mosaic virus, 2003, Plant Physiology
Cadmium blocks viral invasion in plants, 2002, Nature Cell Biology
Virulence and differential local and systemic spread of Cucumber mosaic virus in tobacco are affected by the CMV 2b protein, 2002, Molecular Plant-Microbe Interactions
Salicylic acid has cell-specific effects on Tobacco mosaic virus replication and cell-to-cell movement, 2002, Plant Physiology
Virulence and differential local and systemic spread of cucumber mosaic virus in tobacco are affected by the CMV 2b protein, 2002, Molecular Plant-Microbe Interactions
Signal transduction in resistance to plant viruses, 2001, European Journal of Plant Pathology
Characteristics of salicylic acid-induced delay in disease caused by a necrotrophic fungal pathogen in tobacco, 2000, Physiological and Molecular Plant Pathology
Salicylic acid has a role in regulating gene expression during leaf senescence, 2000, The Plant Journal
Salicylic acid-induced resistance to viruses and other pathogens: A parting of the ways, 1999, Trends in Plant Sciences
Salicylic acid can induce resistance to plant virus movement, 1998, Molecular Plant-Microbe Interactions
Ultraviolet-B-induced responses in Arabidopsis thaliana: Role of salicylic acid and reactive oxygen species in the regulation of transcripts encoding photosynthetic and acidic pathogenesis-related proteins, 1998, Plant, Cell and Environment
Salicylic acid interferes with tobacco mosaic virus replication via a novel, salicylhydroxamic acid-sensitive mechanism, 1997, The Plant Cell
Comparison of cytokinin production in vitro by Pyrenopeziza brassicae with other plant pathogens, 1997, Physiological and Molecular Plant Pathology
Changes in patterns of protein synthesis during haustorial development of Striga hermonthica (Del.) benth seedlings, 1995, Journal of Experimental Botany
Cadmium blocks viral invasion in plants, 2002, Nature Cell Biology
Virulence and differential local and systemic spread of Cucumber mosaic virus in tobacco are affected by the CMV 2b protein, 2002, Molecular Plant-Microbe Interactions
Salicylic acid has cell-specific effects on Tobacco mosaic virus replication and cell-to-cell movement, 2002, Plant Physiology
Virulence and differential local and systemic spread of cucumber mosaic virus in tobacco are affected by the CMV 2b protein, 2002, Molecular Plant-Microbe Interactions
Signal transduction in resistance to plant viruses, 2001, European Journal of Plant Pathology
Characteristics of salicylic acid-induced delay in disease caused by a necrotrophic fungal pathogen in tobacco, 2000, Physiological and Molecular Plant Pathology
Salicylic acid has a role in regulating gene expression during leaf senescence, 2000, The Plant Journal
Salicylic acid-induced resistance to viruses and other pathogens: A parting of the ways, 1999, Trends in Plant Sciences
Salicylic acid can induce resistance to plant virus movement, 1998, Molecular Plant-Microbe Interactions
Ultraviolet-B-induced responses in Arabidopsis thaliana: Role of salicylic acid and reactive oxygen species in the regulation of transcripts encoding photosynthetic and acidic pathogenesis-related proteins, 1998, Plant, Cell and Environment
Salicylic acid interferes with tobacco mosaic virus replication via a novel, salicylhydroxamic acid-sensitive mechanism, 1997, The Plant Cell
Comparison of cytokinin production in vitro by Pyrenopeziza brassicae with other plant pathogens, 1997, Physiological and Molecular Plant Pathology
Changes in patterns of protein synthesis during haustorial development of Striga hermonthica (Del.) benth seedlings, 1995, Journal of Experimental Botany
Teaching and Supervisions
Teaching:
2024/2025:
- Metabolomics data analysis - Training Lead, Trainer
2023/2024:
- Introduction to Metabolomics - Training Lead, Trainer
2018/2019:
- An introduction to metabolomics and its application in life-sciences - Training Lead, Trainer
2017/2018:
- An introduction to metabolomics and its application in life-sciences - Training Lead, Trainer
2016/2017:
- An introduction to metabolomics and its application in life-sciences - Training Lead, Trainer
2015/2016:
- An introduction to metabolomics and its application in life-sciences - Training Lead, Trainer
2014/2015:
- An introduction to metabolomics - Training Lead, Trainer
