Single-cell multi-omics profiling links dynamic DNA methylation to cell fate decisions during mouse early organogenesis
SJ Clark, R Argelaguet, T Lohoff, F Krueger, D Drage, B Göttgens, ...
Genome Biology 23 (1), 1-20
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2022 |
Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation
M Arez, M Eckersley-Maslin, T Klobučar, J von Gilsa Lopes, F Krueger, ...
Nature Communications 13 (1), 1-20
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2022 |
Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function
M Ravichandran, D Rafalski, CI Davies, O Ortega-Recalde, X Nan, ...
Science Advances 8 (36), eabm2427
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2022 |
Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses
J Rodríguez-Ubreva, A Arutyunyan, MJ Bonder, D Pino-Molina, SJ Clark, ...
Nature communications 13 (1), 1-18
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2022 |
8C-like cells capture the human zygotic genome activation program in vitro
J Taubenschmid-Stowers, M Rostovskaya, F Santos, S Ljung, ...
Cell stem cell 29 (3), 449-459. e6
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2022 |
Stimulation of adaptive gene amplification by origin firing under replication fork constraint
AJ Whale, M King, RM Hull, F Krueger, J Houseley
Nucleic acids research 50 (2), 915-936
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2022 |
Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes
M Suriyalaksh, C Raimondi, A Mains, A Segonds-Pichon, S Mukhtar, ...
Iscience 25 (1), 103663
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2022 |
NANOGP1, a tandem duplicate of NANOG, exhibits partial functional conservation in human naive pluripotent stem cells
K Maskalenka, G Alagoz, F Krueger, J Wright, M Rostovskaya, A Nakhuda, ...
bioRxiv
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2022 |
Decoding gene regulation in the mouse embryo using single-cell multi-omics
R Argelaguet, T Lohoff, JG Li, A Nakhuda, D Drage, F Krueger, L Velten, ...
bioRxiv
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2022 |
Genome-wide analysis of DNA replication and DNA double-strand breaks using TrAEL-seq
N Kara, F Krueger, P Rugg-Gunn, J Houseley
PLoS biology 19 (3), e3000886
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2021 |
Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle
JA Halsall, S Andrews, F Krueger, CE Rutledge, G Ficz, W Reik, ...
Scientific reports 11 (1), 1-19
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2021 |
The distinct effects of MEK and GSK3 inhibition upon the methylome and transcriptome of mouse embryonic stem cells
J Spindel, C Krueger, F Krueger, EK Papachristou, K Kishore, ...
bioRxiv
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2021 |
Single-Cell Atlas of Common Variable Immunodeficiency reveals germinal center-associated epigenetic dysregulation in B cell responses
J Rodríguez-Ubreva, A Arutyunyan, MJ Bonder, L Del Pino-Molina, ...
bioRxiv
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2021 |
Modelling human zygotic genome activation in 8C-like cells in vitro
J Taubenschmid-Stowers, M Rostovskaya, F Santos, S Ljung, ...
bioRxiv
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2021 |
Inference of emergent spatio-temporal processes in single-cell genomics
F Olmeda, T Lohoff, S Clark, L Benson, F Krueger, W Reik, S Rulands
APS March Meeting Abstracts 2021, S13. 009
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2021 |
Inference of emergent spatio-temporal processes from single-cell sequencing reveals feedback between de novo DNA methylation and chromatin condensates
F Olmeda, T Lohoff, SJ Clark, L Benson, F Krüger, W Reik, S Rulands
bioRxiv, 2020.12. 30.424823
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2021 |
DNA methylation changes during preimplantation development reveal inter-species differences and reprogramming events at imprinted genes
E Ivanova, S Canovas, S Garcia-Martínez, R Romar, JS Lopes, D Rizos, ...
Clinical epigenetics 12 (1), 1-18
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2020 |
Correction to: DNA methylation changes during preimplantation development reveal interspecies differences and reprogramming events at imprinted genes
E Ivanova, S Canovas, S Garcia-Martínez, R Romar, JS Lopes, D Rizos, ...
Clinical Epigenetics 12 (1), 1-1
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2020 |
IMPLICON: an ultra-deep sequencing method to uncover DNA methylation at imprinted regions
T Klobučar, E Kreibich, F Krueger, M Arez, D Pólvora-Brandão, ...
Nucleic acids research 48 (16), e92-e92
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2020 |
Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions
O Thompson, F von Meyenn, Z Hewitt, J Alexander, A Wood, ...
Nature communications 11 (1), 1-14
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2020 |