Evolutionary biologist interested in the origins of evolutionary novelty and molecular basis of adaptation.
Biography
Education
University of Cambridge
PhD, Biological Sciences 2012 - 2016
DTU - Technical University of Denmark
MSc, Systems Biology 2009 - 2012
MSc thesis: "Effects of synonymous mutations on phenotype"MSc thesis: "Effects of synonymous mutations on phenotype"
DTU - Technical University of Denmark
Computer Science 2008 - 2009
Exchange student
Publications
Key publications:
| TRIM7 restricts Coxsackievirus and norovirus infection by detecting the C-terminal glutamine generated by 3C protease processing
J Luptak, DL Mallery, AS Jahun, A Albecka, D Clift, O Ather, G Slodkowicz, ...
Viruses 14 (8), 1610
|
2022 | |
| Stability of SARS-CoV-2 phylogenies
Y Turakhia, N De Maio, B Thornlow, L Gozashti, R Lanfear, CR Walker, ...
PLoS genetics 16 (11), e1009175
|
2020 | |
| Ribosome collisions trigger cis-acting feedback inhibition of translation initiation
S Juszkiewicz, G Slodkowicz, Z Lin, P Freire-Pritchett, SY Peak-Chew, ...
Elife 9, e60038
|
2020 | |
| Masking strategies for SARS-CoV-2 alignments
N De Maio, C Walker, R Borges, L Weilguny, G Slodkowicz, N Goldman
|
2020 | |
| Issues with SARS-CoV-2 sequencing data
N De Maio, C Walker, R Borges, L Weilguny, G Slodkowicz, N Goldman
|
2020 | |
| Integrated structural and evolutionary analysis reveals common mechanisms underlying adaptive evolution in mammals
G Slodkowicz, N Goldman
Proceedings of the National Academy of Sciences 117 (11), 5977-5986
|
2020 | |
| Issues with SARS-CoV-2 sequencing data. 2020
N De Maio, C Walker, R Borges, L Weilguny, G Slodkowicz, N Goldman
|
2020 | |
| Rare missense variants in the human cytosolic antibody receptor preserve antiviral function
J Zeng, G Slodkowicz, LC James
Elife 8, e48339
|
2019 | |
| Integrated evolutionary and structural analysis reveals xenobiotics and pathogens as the major drivers of mammalian adaptation
G Slodkowicz, N Goldman
bioRxiv, 762690
|
2019 | |
| A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection
SC Wright, P Kozielewicz, M Kowalski-Jahn, J Petersen, CF Bowin, ...
Nature communications 10 (1), 667
|
2019 | |
| From prioritisation to understanding: mechanistic predictions of variant effects
G Slodkowicz, MM Babu
Molecular Systems Biology 14 (12), e8741
|
2018 | |
| TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination
M Bottermann, S Foss, LM van Tienen, M Vaysburd, J Cruickshank, ...
Proceedings of the National Academy of Sciences 115 (41), 10440-10445
|
2018 | |
| A scored human protein-protein interaction network to catalyze genomic interpretation
T Li, R Wernersson, RB Hansen, H Horn, J Mercer, G Slodkowicz, ...
Nature methods 14 (1), 61-64
|
2017 | |
| PASP—a whole-transcriptome poly (A) tail length determination assay for the Illumina platform
B Sipos, AM Stütz, G Slodkowicz, T Massingham, J Korbel, N Goldman
bioRxiv, 060004
|
2016 | |
| Structural and functional determinants of protein evolution
G Slodkowicz
University of Cambridge
|
2016 | |
| The human blood DNA methylome displays a highly distinctive profile compared with other somatic tissues
R Lowe, G Slodkowicz, N Goldman, VK Rakyan
Epigenetics 10 (4), 274-281
|
2015 | |
| Transcriptional diversity during lineage commitment of human blood progenitors
L Chen, M Kostadima, JHA Martens, G Canu, SP Garcia, E Turro, ...
Science 345 (6204), 1251033
|
2014 | |
| Realistic simulations reveal extensive sample-specificity of RNA-seq biases
B Sipos, G Slodkowicz, T Massingham, N Goldman
arXiv preprint arXiv:1308.3172
|
2013 | |
| DTU Synthetic Promoter Library Standard
P Fortuna, T Trolle, MM Borch, A Haugaard, MF Kjærgaard, LB Iversen, ...
|
2010 |
Teaching and Supervisions
Teaching:
2019/2020:
- Molecular Phylogenetics - Trainer
2018/2019:
- Molecular Phylogenetics - Trainer
2017/2018:
- Molecular Phylogenetics - Trainer
2016/2017:
- Molecular Phylogenetics - Trainer
2015/2016:
- Molecular Phylogenetics - Trainer
