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Research Informatics Training

 

I am currently interested in RdRp evolution and diversity as well as molecular biology of RNA viruses. I am scripting in Python and use other bioinformatic approaches to find and characterise new and novel viruses in different datasets.

Biography

Ingrida Olendraite is a virology researcher at the University of Cambridge, where she has also gained her PhD in Computational Molecular Virology (prof. Firth group). Her main research focus is novel RNA virus discovery and molecular biology. Before Cambridge, Ingrida studied Genetics of Human Disease at University College London (MSc) and Molecular Biology at Vilnius University (BA). For the BA project, Ingrida worked on RNA methylation (prof. Klimasauskas group, Institute of Biotechnology), while the MSc project was focusing on training artificial neural networks (Deep Learning) to make a model for protein binding to DNA while facilitating gene expression (prof. Luscombe group, The Francis Crick institute). During COVID-19 pandemic, Ingrida was invited to an advisory council for Lithuanian prime minister and initiated the SARS-CoV-2 sequencing project in Lithunia.


 

Publications

Key publications: 

 

Identification of RNA Virus-Derived RdRp Sequences in Publicly Available Transcriptomic Data Sets.

Molecular biology and evolution
2023-04-01 | Journal article | Author
Contributors: Ingrida Olendraite; Katherine Brown; Andrew E Firth

Emergence and spread of SARS-CoV-2 lineage B.1.620 with variant of concern-like mutations and deletions.

Nature communications
2021-10-01 | Journal article
Contributors: Gytis Dudas; Samuel L. Hong; Potter BI; Sebastien Calvignac-Spencer; Niatou-Singa FS; Tombolomako TB; Fuh-Neba T; Vickos U; Ulrich M; Fabian Leendertz et al.

A case for a negative-strand coding sequence in a group of positive-sense RNA viruses

Virus Evolution
2020 | Journal article
Part of ISSN: 2057-1577

Mining‌ ‌Diverse‌ ‌and‌ ‌Novel‌ ‌RNA‌ ‌Viruses‌‌ in‌ ‌Transcriptomic‌ ‌Datasets‌ ‌
 
2020-12-31 | Dissertation/Thesis
Contributors: Ingrida Olendraite

The International Virus Bioinformatics Meeting 2020.
Viruses
2020-12-06 | Journal article
Contributors: Franziska Hufsky; Niko Beerenwinkel; Meyer IM; Simon Roux; Georgia Cook; Cormac Kinsella; Kevin Lamkiewicz; Marquet M; David F. Nieuwenhuijse; Olendraite I et al.

ICTV Virus Taxonomy Profile: Solinviviridae

Journal of General Virology
2019-05-01 | Journal article
Part of ISSN: 0022-1317
Part of ISSN: 1465-2099

ICTV Virus Taxonomy Profile: Polycipiviridae

Journal of General Virology
2019-04-01 | Journal article
Part of ISSN: 0022-1317
Part of ISSN: 1465-2099

Discovery of three RNA viruses using ant transcriptomic datasets

Archives of Virology
2018 | Journal article
EID: 2-s2.0-85056327742
Contributors: Kleanthous, E.; Olendraite, I.; Lukhovitskaya, N.I.; Firth, A.E.

Archaeal fibrillarin-Nop5 heterodimer 2′-O-methylates RNA independently of the C/D guide RNP particle

RNA
2017 | Journal article
EID: 2-s2.0-85027549979
Contributors: Tomkuviene, M.; Ličyte, J.; Olendraite, I.; Liutkevičiute, Z.; Clouet-D'Orval, B.; Klimašauskas, S.

Polycipiviridae: A proposed new family of polycistronic picorna-like RNA viruses

Journal of General Virology
2017 | Journal article
EID: 2-s2.0-85029600891
Contributors: Olendraite, I.; Lukhovitskaya, N.I.; Porter, S.D.; Valles, S.M.; Firth, A.E.

 

Teaching and Supervisions

Teaching: 

 

2023/2024:

  • NST PartII BBS Bioinformatics Minor - Trainer

2022/2023:

  • NST PartII BBS Bioinformatics Minor - Trainer
Ingrida Olendraite

Contact Details

Email address: 
Department of Pathology
University of Cambridge
Tennis Court Road
Cambridge
CB2 1QP