Ramy Ragheb, PhD

Propelled by my passion for science (biology in particular), I completed a PhD in Genomics and Bioinformatic in 2016. My project focused on the immune response to infection and its interaction with inflammation. During this time, I was also involved in processing clinical data obtained from thousands of patients being admitted for infection in intensive care. I performed a GWAS (genome wide association studies) in order to highlight genomic markers correlating with a sepsis or a septic shock condition. I joined the Cambridge Stem Cell Institute (Cambridge University) as a PostDoc in Dr Brian Hendrich's lab, during which my research interests evolved. I am now focused on investigating the role of chromatin remodellers in gene expression regulation and transcription. My idea is to better understand how a gene regulatory network (GRN) is established and maintained, and what are the key actors that rules this process. Working in Dr. Brian Hendrich team has been and is still a great opportunity for me to study this fascinating process as well as developing my bioinformatic skills to a high level. In my role as bioinformatician, I have analysed a wide range of data sets, including: ChIP-seq, CUT&RUN, CUT&TAG, bulk RNA-seq and single cell RNA-seq. As the only dry-lab member of the team, I have contributed actively to developing solution based ideas for the team. I have also taught my team mates the fundamentals of bioinformatic techniques (from the theory to practical).