I am a geneticist with a background in plant-parasite genetics, single-cell DNA sequencing, plant genetics and evolution, and mathematics. I use the Linux command line fluently, and I also use R and Python. Most recently, I worked on a method to infer which parent genetic variants were inherited from using epigenetic imprinting.
Biography
PhD Genetics, University of Groningen (2023).
Researcher and Bioinformatician
BC Cancer · Full-time Oct 2018 - Jul 2023 · 4 yrs 10 mos Vancouver, British Columbia, Canada · On-site
I developed analytic and wet lab methods for single-cell DNA sequence data, including methods to:
- Discover and genotype chromosomal inversions (InvertypeR)
- Infer which parent genetic variants came from (parent-of-origin phasing)
- Produce thousands of inexpensive, single-cell DNA sequencing libraries in nanoliter volumes (OP-Strand-seq)
I also published five first-author scientific articles in reputable journals and performed routine processing of DNA sequence data.
MSc Forestry, University of British Columbia (2018).
Field Technician
Publications
Chromosome-Length Haplotypes with StrandPhaseR and Strand-seq
Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq
Cell Genomics
A survey of current methods to detect and genotype inversions
Mapping of sister chromatid exchange events and genome alterations in single cells
Construction of Strand-seq libraries in open nanoliter arrays
InvertypeR: Bayesian inversion genotyping with Strand-seq data
Somatic mutations substantially increase the per‐generation mutation rate in the conifer Picea sitchensis
Teaching and Supervisions
2023/2024:
- Introduction to UNIX and bash - Trainer
