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Research Informatics Training

 

Research Associate, Department of Medicine

Biography

Education

  • UCL

    Doctor of Philosophy - PhD Virology

    2014 - 2017


  • UCL

    Master's degree Evolutionary Biology Distinction

    2013 - 2014


  • UCL

    Bachelor of Science - BS Molecular Biology 1st class honours

    2010 - 2013

Publications

Key publications: 

 

A framework for automated scalable designation of viral pathogen lineages from genomic data
J McBroome, A de Bernardi Schneider, C Roemer, MT Wolfinger, ...
Nature Microbiology, 1-11
  2024
The unified proposal for classification of human respiratory syncytial virus below the subgroup level (preprint)
S Goya, C Ruis, R Neher, A Meijer, A Aziz, A Hinrichs, A von Gottberg, ...
 
  2024
The unified proposal for classification of human respiratory syncytial virus below the subgroup level
S Goya, C Ruis, RA Neher, A Meijer, A Aziz, AS Hinrichs, A von Gottberg, ...
medRxiv, 2024.02. 13.24302237
  2024
A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes
T Sanderson, R Hisner, I Donovan-Banfield, H Hartman, A Løchen, ...
Nature 623 (7987), 594-600
  2023
Mutational spectra are associated with bacterial niche
C Ruis, A Weimann, G Tonkin-Hill, AP Pandurangan, M Matuszewska, ...
Nature Communications 14 (1), 7091
  2023
SARS-CoV-2 evolution in the Omicron era
C Roemer, DJ Sheward, R Hisner, F Gueli, H Sakaguchi, N Frohberg, ...
Nature microbiology 8 (11), 1952-1959
  2023
Impact of transient acquired hypermutability on the inter- and intra-species competitiveness of Pseudomonas aeruginosa
YY On, W Figueroa, C Fan, PM Ho, ÉB Bényei, A Weimann, C Ruis, ...
The ISME Journal 17 (11), 1931-1939
  2023
A lung-specific mutational signature enables inference of viral and bacterial respiratory niche
C Ruis, TP Peacock, LM Polo, D Masone, MS Alvarez, AS Hinrichs, ...
Microbial genomics 9 (5), 001018
  2023
Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes
S Cotton, MP McHugh, R Dewar, JG Haas, K Templeton, SC Robson, ...
Journal of Hospital Infection 135, 28-36
  2023
Automated Agnostic Designation of Pathogen Lineages
J McBroome, A de Bernardi Schneider, C Roemer, MT Wolfinger, ...
bioRxiv, 2023.02. 03.527052
  2023
Identification of a molnupiravir-associated mutational signature in SARS-CoV-2 sequencing databases
T Sanderson, R Hisner, I Donovan-Banfield, H Hartman, A Løchen, ...
medRxiv, 2023.01. 26.23284998
  2023
Automated Agnostic Designation of Pathogen Lineages (preprint)
J McBroome, A de Bernardi Schneider, C Roemer, MT Wolfinger, ...
 
  2023
Identification of a molnupiravir-associated mutational signature in SARS-CoV-2 sequencing databases (preprint)
T Sanderson, R Hisner, T Peacock, C Ruis
 
  2023
Calculating and applying pathogen mutational spectra using MutTui
C Ruis, G Tonkin-Hill, RA Floto, J Parkhill
bioRxiv, 2023.06. 15.545111
  2023
Context-specific emergence and growth of the SARS-CoV-2 Delta variant
JT McCrone, V Hill, S Bajaj, RE Pena, BC Lambert, R Inward, S Bhatt, ...
Nature 610 (7930), 154-160
  2022
Mutational spectra distinguish SARS-CoV-2 replication niches
C Ruis, TP Peacock, LM Polo, D Masone, MS Alvarez, AS Hinrichs, ...
BioRxiv, 2022.09. 27.509649
  2022
Emergence of SARS-CoV-2 omicron lineages BA. 4 and BA. 5 in South Africa
H Tegally, M Moir, J Everatt, M Giovanetti, C Scheepers, E Wilkinson, ...
Nature medicine 28 (9), 1785-1790
  2022
Emergence and widespread circulation of a recombinant SARS-CoV-2 lineage in North America
B Gutierrez, HGC Sánchez, D da Silva Candido, B Jackson, S Fleishon, ...
Cell Host & Microbe 30 (8), 1112-1123. e3
  2022
Mutational spectra analysis reveals bacterial niche and transmission routes
C Ruis, A Weimann, G Tonkin-Hill, AP Pandurangan, M Matuszewska, ...
bioRxiv, 2022.07. 13.499881
  2022
Continued emergence and evolution of Omicron in South Africa: New BA. 4 and BA. 5 lineages
H Tegally, M Moir, J Everatt, M Giovanetti, C Scheepers, E Wilkinson, ...
MedRxiv, 2022.05. 01.22274406
  2022
 

Teaching and Supervisions

Teaching: 

 

2023/2024:

  • Working with Bacterial Genomes - Trainer
Chris Ruis, PhD

Contact Details

Email address: 
Department of Medicine
Jeffrey Cheah Biomedical Centre
Cambridge Biomedical Campus
Puddicombe Way
Cambridge
CB2 0AW