Kate Mellor is a senior staff scientist in the Pathogens and Microbes programme at the Wellcome Sanger Institute and a member of the Global Pneumococcal Sequencing project core team. Her work focuses upon the genomics of Streptococcus pneumoniae, with a particular interest in using longitudinal data to understand the dynamics of acquisition and carriage.
Zachary is an evolutionary biologist investigating the evolution and functions of young genes in pathogenic bacteria and viruses, working as a SEED fellow (Sanger Epidemiological and Evolutionary Dynamics)
PhD-trained microbial geneticist with over 12 years of experience in computational biology, bio-statistics, and analysis of bioactive compounds. Advanced skill in R and BASH, meta-omics data analysis (meta-genomics and meta-transcriptomics) molecular evolution of proteins (Membrane protein, Enzymes, Scaffold protein). I have work experience in 4 different countries (India, Germany, the Czech Republic, and the UK) with colleagues from more than 15 nations.
Most of my work is devoted to genomically characterising Salmonella Paratyphi A with a particular focus on AMR, virulence factors, phylogeny and global distribution of the pathogen. I am also interested in azithromycin resistance within S. Paratyphi A with a focus on the increase of resistance in low-mid-income countries.
Although S. Paratyphi A is the main focus of my research, I am also interested in studying the human gut microbiome.
I am a Senior Research Associate at the Department of Veterinary Medicine of the University of Cambridge and a visiting scientist at the Victor Phillip Dahdaleh Heart & Lung Research Institute (HLRI) where I study Antimicrobial Resistance and Host-pathogen Interactions in Gram negative human pathogens, especially Salmonella Typhimurium, Klebsiella pneumoniae and Mycobacterium abscessus.