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Research Informatics Training

 

I am a Senior Research Associate at the Department of Veterinary Medicine of the University of Cambridge and a visiting scientist at the Victor Phillip Dahdaleh Heart & Lung Research Institute (HLRI) where I study Antimicrobial Resistance and Host-pathogen Interactions in Gram negative human pathogens, especially Salmonella Typhimurium, Klebsiella pneumoniae and Mycobacterium abscessus.
I use several Next Generation Sequencing techniques in the field of functional genomics such as deep transcriptome sequencing (RNA-seq) and transposon directed insertion sequencing (TraDIS), Illumina and Oxford nanopore based whole genome sequencing (WGS) and genome wide association studies (GWAS) as well as wet-lab methods like flow cytometry (FACS) and confocal fluorescence microscopy.

After graduating from the Technical University of Braunschweig/Germany, I joined to lab of Susanne Häussler at the Helmholtz Centre for Infection Research. During my PhD I used deep transcriptomic sequencing (RNA-seq) to study Antimicrobial Resistance in Pseudomonas aeruginosa and Klebsiella pneumoniae. Followed by a short post-doc in the same group where I developed rapid molecular diagnostics to detect hospital outbreaks and antibiotic resistance in several different bacterial species (mainly, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli and Clostridium difficile). In 2017, I took up a post as a postdoctoral fellow in the Parkhill group at the Wellcome Sanger Institute using Functional Genomics (RNA-sequencing and transposon-directed insertion site sequencing, TraDIS) to understand the antimicrobial stress response in the Enterobacteriaceae species Klebsiella, Salmonella and Enterobacter.