Bioinformatics Teaching Associate
Job Role
Bajuna works with Hugo to support the development and delivery of our portfolio of 'omics related courses.
Hours
Monday to Friday, office hours.
Biography
I am a Teaching Associate at the Bioinformatics Training Facility.
I am doing bioinformatics in genomics and also involved with development of computational methods for variant detection and predicting protein structures.
Currently, I am supporting the delivery of bioinformatics related training material to international institutions and organisations in collaboration with the UK Health Security Agency's New Variant Assessment Platform (https://www.gov.uk/guidance/new-variant-assessment-platform). I am also developing and delivering new training materials for the Bioinformatics Training Facility's portfolio of courses, focussing on bioinformatics related training material (e.g. proteomics, metabolomics, metagenomics, transcriptomics etc.).
Previously I was involved with the collaborative project between researchers from the University of Reading, National Institute for Agriculture and Botany (NIAB), and Birmingham University to investigate the mechanism by which Pseudomonas syringae causes canker disease in cherry plants. In that project I was involved with the development of bioinformatics pipeline to analyse large genomic data samples associated with canker cherry disease. I was also involved with IntFOLD project in the University of Reading, which primarily focused on the development of state-of-the-art methods for prediction and optimisation of 3D protein models mainly using machine learning and deep learning methods. In IntFOLD project I was involved particularly with the development of front-end tools and in-house training materials for understanding the 3D protein modelling from amino acid sequences.
Furthermore, I also worked as Bioinformatician for Genomics at the University Reading with the different genomics and post-genomic projects. In genomics I mainly use next generation sequencing (NGS) technique to understand microbial involvements in several aspects such agriculture (e.g biocontrol), energy, poultry and how these do have health impacts on human beings and other species. Generally, my research focuses on developing computational tools for understanding and decode biological data in the postgenomic era.
Publications
McGuffin, L., Shuid, A. N., Kempster, R., Maghrabi, A. H.A., Nealon, J. O., Salehe, B. R., Atkins, J. D. and Roche, D. B. (2018) Accurate template-based modeling in CASP12 using the IntFOLD4-TS, ModFOLD6, and ReFOLD methods. Proteins: Structure, Function, and Bioinformatics, 86. pp. 335-344. ISSN 0887-3585 doi: https://doi.org/10.1002/prot.25360
Salehe, B. R (2017) Predictive tools for the study of variations in ADP platelet responses: implications for personalised CVD risk and prevention strategies. University of Reading.
Salehe, B. R., Jones, C. I., Di Fatta, G. and McGuffin, L. (2017) RAPIDSNPs: A new computational pipeline for rapidly identifying key genetic variants reveals previously unidentified SNPs that are significantly associated with individual platelet responses. PLoS ONE, 12 (4). e0175957. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0175957
McGuffin, L. J., Atkins, J. D., Salehe, B. R., Shuid, A. N. and Roche, D. B. (2015) IntFOLD: an integrated server for modelling protein structures and functions from amino acid sequences. Nucleic Acids Research, 43 (W1). W169-W173. ISSN 1362-4962 doi: https://doi.org/10.1093/nar/gkv236
BR Salehe, LJ McGuffin, CI Jones, G Di Fatta (2014) IDENTIFICATION OF NOVEL GENES ASSOCIATED WITH PLATELET ACTIVATION SIGNALLING PATHWAYS IN HIGH DIMENSIONAL DATA USING AN ALTERNATIVE REGRESSION APPROACH. Heart, 100(4), A2-A4, BMJ Publishing Group Ltd and British Cardiovascular Society.
Teaching and Supervisions
2024/2025:
- Managing bioinformatics software and pipelines - Training Lead, Trainer
- Working on HPC clusters - Training Lead, Trainer
- Protein structure modelling - Training Lead
- Working with Bacterial Genomes - Training Lead, Trainer
2023/2024:
- Working with Bacterial Genomes - Training Lead, Trainer
- Introduction to metagenomics - Trainer
- Introduction to working with UNIX and bash - Trainer
- Introduction to Phylogenetics - Trainer
- Analysis of bulk RNA-seq data - Training Lead, Trainer
- Analysis of expression Proteomics data in R - Trainer
- High Performance Computing: An Introduction - Trainer
2022/2023:
- Analysis of ChIP-seq data - Trainer