Jacqueline Boccacino

Jacqueline is a PhD student at the Wellcome Sanger Institute and the University of Cambridge. Before starting her doctoral studies, she worked as a bioinformatician for a year in Dr. David Adams' Experimental Cancer Genetics group at the Wellcome Sanger Institute. Jacqueline obtained a BSc degree in Molecular Sciences from the University of São Paulo (USP) and carried out undergraduate-level research in the Laboratory of Neurobiology and Stem Cells of the Institute of Biomedical Sciences of USP, under the supervision of Dr. Marilene H. Lopes. As the Sanger Prize 2021 winner, Jacqueline worked as a visiting researcher for 3 months in Dr. Sarah Teichmann's lab. After obtaining her bachelor’s degree, Jacqueline worked as a bioinformatician in Dr. David Adams’ group for a year before pursuing her doctoral degree.

Biography

Education

University of Cambridge

Doctor of Philosophy - PhD, Biological Science Oct 2023 - Sep 2027
- Activities and societies: Member of Gonville & Caius College. Instructor in the Cambridge University Bioinformatics Training Facility
USP - Universidade de São Paulo

Bachelor of Science - BS, Molecular Sciences Aug 2018 - Aug 2022
- Grade: 8.4 (out of 10)
- I was an undergraduate student in the 4-year Molecular Sciences programme of the University of São Paulo (USP). This programme focuses on training researchers with an interdisciplinary background, being divided into two cycles: the basic cycle (years 1 and 2) covers a range of subjects on biology, chemistry, mathematics, physics, and computer science; and the advanced cycle (years 3 and 4) consists of intensive scientific training and research internships along with a flexible schedule comprising courses related to the student's research interests.

Publications

Key publications:

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics

Nature

2024-06-19 | Journal article | Author

DOI: 10.1038/s41586-024-07575-x

Contributors: Rik G.H. Lindeboom; Kaylee Worlock; Lisa M. Dratva; Masahiro Yoshida; David Scobie; Helen Wagstaffe; Laura Richardson; Anna Wilbrey; Josephine L Barnes; Krzysztof Polański et al.

Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas

BMC Cancer

2024-02-13 | Journal article

DOI: 10.1186/s12885-024-11914-6

Part of ISSN: 1471-2407

Contributors: Jacqueline Marcia Boccacino; Rafael dos Santos Peixoto; Camila Felix de Lima Fernandes; Giovanni Cangiano; Paula Rodrigues Sola; Bárbara Paranhos Coelho; Mariana Brandão Prado; Maria Isabel Melo-Escobar; Breno Pereira de Sousa; Shamini Ayyadhury et al.

Unconventional Protein Secretion in Brain Tumors Biology: Enlightening the Mechanisms for Tumor Survival and Progression

Frontiers in Cell and Developmental Biology

2022-06-15 | Journal article

DOI: doi.org/10.3389/fcell.2022.907423

Extracellular vesicles throughout development: a potential roadmap for emerging glioblastoma therapies

Seminars in Cell & Developmental Biology

2022-06-10 | Journal article

DOI: 10.1016/j.semcdb.2022.05.027

Multifaceted WNT signaling at the crossroads between epithelial-mesenchymal transition and autophagy in glioblastoma

Frontiers in Oncology

2020-11-12 | Journal article

DOI: 10.3389/fonc.2020.597743

A New Take on Prion Protein Dynamics in Cellular Trafficking

International Journal of Molecular Sciences

2020-10-20 | Journal article

DOI: 10.3390/ijms21207763

Contributors: Rodrigo Nunes Alves; Rebeca Piatniczka Iglesia; Mariana Brandão Prado; Maria Isabel Melo Escobar; Jacqueline Marcia Boccacino; Camila Felix de Lima Fernandes; Bárbara Paranhos Coelho; Ailine Cibele Fortes; Marilene Hohmuth Lopes

Prion Protein at the Leading Edge: Its Role in Cell Motility

International Journal of Molecular Sciences

2020-09-12 | Journal article

DOI: 10.3390/ijms21186677

Contributors: Mariana Brandão Prado; Maria Isabel Melo Escobar; Rodrigo Nunes Alves; Bárbara Paranhos Coelho; Camila Felix de Lima Fernandes; Jacqueline Marcia Boccacino; Rebeca Piatniczka Iglesia; Marilene Hohmuth Lopes

Teaching and Supervisions

Teaching:

2024/2025:

Introduction to the Unix command line - Trainer
Introduction to Python - Trainer
Introduction to R - Trainer
Working on HPC clusters - Trainer
Reproducible Research with R - Trainer

2023/2024:

Analysis of single cell RNA-seq data - Trainer

Biography

Education

Publications

Human SARS-CoV-2 challenge uncovers local and systemic response dynamics

Teaching and Supervisions

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